In clinical research having a well-run, compliant study is a top priority. Ensuring patients are protected and resulting data has integrity, it’s important to be experts in all aspects of your study. If your trial involves imaging, understanding how to get the most out of your data is not only smart- it’s cost effective. From a recent article published on GEN - Genetic Engineering & Biotechnology news, here are nine tips to help bring products to market faster with these ways of optimizing preclinical imaging:
- Connect preclinical imaging specialists with those from other areas within the development process (preclinical, translational, and clinical development) to evaluate the translatability of model components
- Consider all aspects of a modeling strategy
- Ask for prior data from the group performing the study
- Co-validate new paradigms to establish new methodologies and design studies in a cost-effective way
- Employ “test-retest” measures in order to estimate within group and within subject variations
- Discuss the possibilities as well as the limitations of the disease model in question. In the same context, discuss openly and decide beforehand the exclusion criteria (if any) and when/where/if to replace subjects in the study
- High throughput and high quality
- Use multiple time-point imaging to allow for better insight into disease pathology and drug effect or lack of effect
- Address all questions using a combination of methods—preferably from one scanning period within each study subject
In addition to these nine tips, we would like to add one more to the list…
- Ensure ongoing training. When imaging is introduced to a clinical trial, a new layer of complexity is added and it’s vital to keep the entire study team up-to-date with how to manage the challenges of a clinical trial.
Interested in learning more about imagining in clinical trials and the unique compliance challenges this situation creates? Register for IMARC Research and ImageIQ’s free webinar on this hot-topic. This complementary webinar will take place on Wednesday, December 5th at 11am EST.
Photo Credit: judy_breck