Obtaining useful and meaningful data is one of the goals of any clinical trial. However, in order to attain the necessary data, subject participation in clinical trials is paramount as subjects are the heart and soul of a clinical trial. One of the keys to a successful clinical trial, no matter the stage or trial type, whether it is a drug or device study, is meeting subject enrollment requirements. Understanding how the general public views clinical trials and how clinical research professionals might shape that opinion, is vital.